Table 2.
The percentage of clinical isolate of P.aeruginosa growth inhibition in the presence of the tested antibiotics alone and in combination with ZnO NPs at subinhibitory concentrations (1/2 – 1/16 × MIC)
| Antibiotic Concentration (μg/ml) | ZnO NPs Concentration (μg/ml) |
||||
|---|---|---|---|---|---|
| 0 | 23.4 | 46.8 | 93.7 | 187.5 | |
| Ceftazidime | |||||
| 0 | 0 | 32.48 ± 2.08 | 50.57 ± 3.38 | 76.78 ± 3.03 | 93.29 ± 0.82 |
| 1 | 12.29 ± 2.83 | 46.52 ± 0.47 | 95.49 ± 1.48 | 98.32 ± 0.32 | 99.8 ± 0.75 |
| 2 | 22.96 ± 1.12 | 93.57 ± 1.60 | 98.12 ± 0.12 | 98.88 ± 0.11 | 100 |
| 4 | 47.52 ± 7.69 | 99.20 ± 0.46 | 100 | 100 | 100 |
| Tobramycin | |||||
| 0 | 0 | 42.44 ± 1.59 | 57.54 ± 0.67 | 79.24 ± 1.61 | 93.15 ± 0.60 |
| 0.25 | 7.68 ± 2.76 | 81.03 ± 3.07 | 92.24 ± 1.95 | 97.12 ± 0.24 | 97.12 ± 0.24 |
| 0.5 | 25.10 ± 3.24 | 85.45 ± 1.46 | 96.51 ± 0.80 | 100 | 100 |
| 1 | 62.31 ± 3.03 | 92.03 ± 0.82 | 100 | 100 | 100 |
| Ciprofloxacin | |||||
| 0 | 0 | 45.01 ± 2.64 | 54.05 ± 1.45 | 75.87 ± 2.37 | 94.81 ± 1.65 |
| 0.0625 | 42.51 ± 3.48 | 74.66 ± 1.16 | 94.15 ± 0.82 | 98.59 ± 0.09 | 98.57 ± 0.25 |
| 0.125 | 78.40 ± 6.10 | 94.66 ± 0.50 | 100 | 100 | 100 |
| 0.25 | 96.96 ± 0.87 | 100 | 100 | 100 | 100 |
ZnO NPs: ZnO nanoparticles