Effect of GPM on caspase-3 and caspase-9 expression levels and the release of AIF and Cyt c from the mitochondria into the cytosol. *P<0.05, **P<0.01 vs. control group. Cells were treated with 0.003 mg/ml 5-Fu, 0.06 mg/ml GPML or 0.08 mg/ml GPMH. *P<0.05, **P<0.01 vs. control group. GPM, gecko peptides mixture; 5-Fu, fluorouracil; AIF, apoptosis-inducing factor; Cyt c, cytochrome c.