Table 4.

Hazard Analysis for 7-year Follow-up

	Unadjusted			Multivariable-adjusteda
	Hazards Ratio	95% CI	p-value	Hazards Ratio	95% CI	p-value
LDL Cholesterol
175+ mg/dL	reference			reference
153-174 mg/dL	1.11	0.91-1.31	0.25	1.19	0.99-1.43	0.06
134-152 mg/dL	1.08	0.91-1.27	0.43	1.17	0.97-1.40	0.09
114-133 mg/dL	1.07	0.91-1.27	0.42	1.10	0.91-1.32	0.32
<114 mg/dL	1.27	1.08-1.49	0.0039	1.26	1.05-1.50	0.012
HDL Cholesterol
66+ mg/dL	reference			reference
56 – 66 mg/dL	1.04	0.90-1.21	0.60	1.02	0.86-1.20	0.86
50 - 56 mg/dL	1.04	0.88-1.22	0.64	0.93	0.78-1.11	0.44
43 – 50 mg/dL	1.00	0.85-1.17	0.98	0.83	0.70-1.00	0.05
< 43 mg/dL	1.09	0.93-1.29	0.30	0.81	0.67-0.98	0.034
Total Cholesterol
260+ mg/dL	reference			reference
236 – 259 mg/dL	1.03	0.87-1.22	0.74	1.13	0.94-1.35	0.21
216 – 235 mg/dL	1.12	0.95-1.32	0.17	1.20	1.00-1.44	0.05
195 - 215 mg/dL	1.06	0.89-1.25	0.52	1.09	0.91-1.31	0.37
< 195 mg/dL	1.18	1.00-1.39	0.05	1.14	0.95-1.36	0.17
Triglycerides
185+ mg/dL	reference			reference
136 – 184 mg/dL	0.94	0.80-1.10	0.44	0.97	0.81-1.15	0.70
106 – 135 mg/dL	0.91	0.78-1.07	0.27	1.01	0.85-1.20	0.95
80 – 105 mg/dL	0.93	0.79-1.09	0.37	1.05	0.88-1.26	0.56
< 80 mg/dL	0.81	0.69-0.96	0.014	0.97	0.80-1.17	0.74

^aAdjusted for WHI trial arm, BMI, lipid-lowering medication, blood pressure, smoking status, coronary heart disease, stroke, peripheral artery disease, age, U.S. region, ethnicity, marital status, health insurance, alcohol consumption, leisure-time physical activity, cancer, income, education, diabetes, thyroid disease, and colitis