Table 1.
Summary of laboratory findings for FBS, CRP, IL-6, TNF-alpha, and adiponectin levels
| Week | MF | HFCD | MF + DEN | HFCD + DEN | |
|---|---|---|---|---|---|
| FBS (mg/dl) | 4 | 211.3 ± 41.7 | 297.5 ± 24.6 | 191.0 ± 11.2 | 282.3 ± 26.5 |
| 8 | 149.6 ± 30.9 | 174.2 ± 32.9 | 177.0 ± 64.9 | 167.6 ± 31.3 | |
| 12 | 167.6 ± 41.6 | 241.6 ± 32.4 | 152.0 ± 24.2 | 273.4 ± 31.5 | |
| 16 | 109.8 ± 11.4 | 245.0 ± 46.4 | 112.8 ± 8.7 | 189.8 ± 52.5 | |
| 20 | 188.4 ± 14.6 | 263.2 ± 36.0 | 172.0 ± 36.7 | 242.0 ± 14.4 | |
| 24 | 165.2 ± 23.9 | 265.2 ± 6.5 | 205.3 ± 32.5 | 249.4 ± 24.2 | |
| CRP (ng/ml) | 4 | 4552.6 ± 2533.3 | 3756.8 ± 1366.4 | 4284.9 ± 2261.0 | 4915.4 ± 1697.0 |
| 8 | 5803.1 ± 1368.7 | 13324.9 ± 7100.6 | 5837.7 ± 2422.0 | 6568.3 ± 3827.0 | |
| 12 | 2412.0 ± 211.8 | 2505.3 ± 517.7 | 2465.9 ± 170.5 | 2427.1 ± 337.3 | |
| 16 | 2080.4 ± 756.5 | 3065.7 ± 1047.4 | 2801.3 ± 457.0 | 3002.1 ± 599.5 | |
| 20 | 2125.1 ± 306.9 | 3170.3 ± 711.8 | 2185.4 ± 256.3 | 3293.4 ± 416.6 | |
| 24 | 2227.6 ± 613.8 | 3143.3 ± 393.3 | 2044.0 ± 349.9 | 3686,7 ± 481.2 | |
| IL-6 (pg/ml) | 4 | 0.2 ± 0.3 | 1.3 ± 1.5 | 0.3 ± 0.5 | 0.9 ± 1.3 |
| 8 | 0.5 ± 0.5 | 1.8 ± 1.5 | 0.6 ± 0.7 | 0.9 ± 1.2 | |
| 12 | 0.8 ± 0.5 | 1.1 ± 0.7 | 1.1 ± 0.8 | 2.0 ± 1.5 | |
| 16 | 1.3 ± 0.6 | 2.9 ± 1.2 | 1.2 ± 0.8 | 0.9 ± 0.2 | |
| 20 | 1.6 ± 1.2 | 1.3 ± 0.8 | 1.4 ± 0.9 | 1.6 ± 0.9 | |
| 24 | 2.1 ± 1.3 | 4.2 ± 1.8 | 2.2 ± 4.5 | 1.6 ± 0.3 | |
| TNF-alpha (pg/ml) | 4 | N.D. | 20.7 ± 28.9 | N.D. | 6.2 ± 12.0 |
| 8 | 1.8 ± 3.9 | 270.9 ± 297.5 | 5.0 ± 7.1 | 134.6 ± 153.7 | |
| 12 | 2.2 ± 2.8 | 0.4 ± 0.9 | 0.9 ± 2.0 | 1.9 ± 3.1 | |
| 16 | 0.1 ± 0.1 | 3.4 ± 4.8 | 0.1 ± 0.3 | N.D. | |
| 20 | 1.2 ± 1.6 | 2.0 ± 2.2 | 1.4 ± 1.4 | 1.4 ± 1.3 | |
| 24 | 3.8 ± 6.4 | 5.8 ± 3.0 | 3.5 ± 5.2 | 0.5 ± 1.2 |
The data are shown as the mean ± standard deviation. Each group contained five mice. FBS fasting blood sugar, CRP C-reactive protein, IL interleukin, TNF-alpha tumor necrosis factor-alpha