Table 4.
Summary of computed tomography findings, rate of positive findings, tumor number, and tumor size from 12 to 24 weeks
| Week | MF | HFCD | MF + DEN | HFCD + DEN | |
|---|---|---|---|---|---|
| Mice with positive findings, n (%) | 12 | 0 | 0 | 0 | 0 |
| 16 | 0 | 0 | 0 | 1/5 (20 %) | |
| 20 | 0 | 1/5 (20 %) | 0 | 5/5 (100 %) | |
| 24 | 0 | 0 | 1/5 (20 %) | 5/5 (100 %) | |
| Tumor number | 12 | 0 | 0 | 0 | 0 |
| 16 | 0 | 0 | 0 | 5 | |
| 20 | 0 | 6 | 0 | 10.0 ± 5.4 | |
| 24 | 0 | 0 | 1 | 8.8 ± 5.4 | |
| Tumor size (mm) | 12 | ||||
| 16 | 0.6 ± 0.4 | ||||
| 20 | 0.8 ± 0.2 | 1.6 ± 0.8 | |||
| 24 | 2.2 | 2.9 ± 2.8 |
Data are shown as the mean ± standard deviation. Data in bold indicate a significant difference (p < 0.05) between the standard diet (MF) group and the other groups for each month. HFCD high-fat choline-deficient diet, DEN diethylnitrosamine