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. 2016 May 11;12(1):279–287. doi: 10.3892/etm.2016.3333

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — BGP levels in the six groups. Compared with the sham-operated group, BGP levels in the OVX group increased significantly (P<0.05). Compared with OVX group, levels of BGP in the positive group (P<0.01), and the L-ICA, M-ICA and H-ICA groups were significantly reduced (P<0.05). *P<0.05 vs. sham-operated; ^▲P<0.05 and ^▲▲P<0.01 vs. OVX. BGP, bone Gla protein; OVX, ovariectomy; ICA, icariin; Sham, sham-operated; Positive, treated with alendronate sodium; L-ICA, low dose ICA (125 mg/kg/day); M-ICA, medium dose ICA (250 mg/kg/day); H-ICA, high dose ICA (500 mg/kg/day).