Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 May 11;12(1):279–287. doi: 10.3892/etm.2016.3333

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 4. — Morphometric analysis. (A) Tb.N and Tb.Th decreased significantly in the OVX group compared with the sham group (P<0.01). Compared with the OVX group, the M-ICA group had significantly increased Tb.N and Tb.Th (P<0.05), while Tb.Sp decreased significantly (P<0.05), whereas in the L-ICA group, Tb.Th increased significantly and Tb.Sp decreased significantly (P<0.05). *P<0.05, **P<0.01 vs. sham-operated; ^▲P<0.05 vs. OVX. (B) Micro-computed tomography analysis for the (a) sham, (b) OVX, (c) positive, (d) L-ICA, (e) M-ICA and (f) H-ICA groups. In comparison with the sham group, the bone trabecula is loose, fractured and exhibits loss in the OVX group. Following oral administration of ICA, the number of bone trabecula was clearly increased and the bone trabecula was more densely concatenated than that in the OVX group. Tb.N, trabecular number; Tb.Th, trabecular thickness; Tb.Sp, trabecular separation; OVX, ovariectomy; ICA, icariin; Sham, sham-operated; Positive, treated with alendronate sodium; L-ICA, low dose ICA (125 mg/kg/day); M-ICA, medium dose ICA (250 mg/kg/day); H-ICA, high dose ICA (500 mg/kg/day).