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. 2016 Jun 13;16:281. doi: 10.1186/s12879-016-1636-6

Table 3.

Characteristics of eight included studies published between January 1997 and May 2015

Study Characteristics Methods Results
Study and Year Location Time Period Study Population Notification to Public Health Design Referent Data of Diagnosed Cases Diagnostic criteria Consistent with surveillance criteria and possible effect % Report N
Backer HD et al. 2001 [34] California, US 1997 Kaiser Permanente Northern California members Mandatory dual reporting Data Linkage Laboratory Tests Positive IgM HAV antibody No;
Under-estimate completeness
88.4 % 402
Boehmer TK et al. 2011 [35] Colorado, US 2003–2005 Population-based Mandatory dual reporting Data Linkage Inpatient hospital discharges and medical chart review ICD-9-CM codes 070.0 and 070.1 with review using surveillance definition Yes 67 % 6
Klompas M et al. 2008 [36] Massachu-setts, US June 2006–July 2007 Patients of a multi-specialty group practice of 35 clinics Not described Data Linkage Electronic medical records with e-support for public health system (ESP) ALT or AST >2 times upper normal limit, or ICD-9 code 782.4 for jaundice, and positive IgM HAV antibody No;
Over-estimate
25 % 4
Matin N et al. 2006 [40] England (North East and East Midlands), UK 2002 and 2003 Population-based Mandatory reporting by physicians; voluntary reporting by laboratories with good participation CRC 1. Cases identified by local public health, 2. laboratory tests and 3. genotyping results Not described Unclear 81.7 % (outbreak a) and 27.8 % (outbreak b) 236 and 1107
Overhage JM et al. 2008 [39] Indiana-
polis, Indiana, US
First quarter of 2001 Population-based Mandatory dual reporting Data Linkage Hospital infection-control databases (IC), and an electronic laboratory reporting (ELR) database Not described; system scans test results labels for a match to CDC notifiable condition mapping tables Unclear 4.0 % (IC, study a) and 97.3 % (ELR, study b) 150
Roels TH et al. 1998 [37] Wisconsin, US 1995 Population-based Mandatory dual reporting Data Linkage/Compar-ison Laboratory Tests Positive IgM HAV antibody No;
Under-estimate
74 % 156
Sickbert-Bennett EE et al. 2011 [41] North Carolina, US 1995–2006 (excl. 1998, 1999) Population-based Mandatory reporting by physicians; dual reporting starting 1998 Data Linkage Inpatient hospital discharges and medical chart review ICD-9-CM
(code not specified) with review using surveillance definition
Yes 40.02 % corrected 67
Simmons G et al. 2002 [38] Auckland, New Zealand 2000 Population-based Mandatory reporting by physicians; some laboratories Data Linkage Laboratory Tests Positive IgM HAV antibody No;
Under-estimate
65 % 54

US United States, IgM immunoglobulin M, HAV hepatitis A virus, ICD international classification of diseases, ALT alanine aminotransferase, AST asparatate aminotransferase, UK United Kingdom, CRC capture-recapture methods, n/a not available