Table I.
TNFAIP8 expression | |||||||
---|---|---|---|---|---|---|---|
Cases | Positive | Negative | |||||
Variable | n | n | % | n | % | χ2 | P-value |
Total cases | 106 | 50 | 47.2 | 56 | 52.8 | ||
Gender | 1.500 | 0.221 | |||||
Male | 70 | 36 | 51.4 | 34 | 48.6 | ||
Female | 36 | 14 | 38.9 | 22 | 61.1 | ||
Age (years) | |||||||
≥60 | 74 | 34 | 45.9 | 40 | 54.1 | 0.147 | 0.701 |
<60 | 32 | 16 | 50.0 | 16 | 50.0 | ||
Pathological grading | 4.413 | 0.110 | |||||
Well differentiated | 14 | 3 | 21.4 | 11 | 78.6 | ||
Moderately differentiated | 24 | 13 | 54.2 | 11 | 45.8 | ||
Poorly differentiated | 68 | 34 | 50.0 | 34 | 50.0 | ||
Tumor size (maximum diameter) | 0.482 | 0.488 | |||||
≤5.0 cm | 31 | 14 | 45.2 | 17 | 54.8 | ||
>5.0 cm | 75 | 37 | 49.3 | 38 | 51.7 | ||
Vascular invasion | 9.974 | 0.002 | |||||
Yes | 66 | 39 | 59.1 | 27 | 40.9 | ||
No | 40 | 11 | 27.5 | 29 | 72.5 | ||
CA72-4 | 22.718 | <0.001 | |||||
≤6.9 KU/l | 47 | 10 | 21.2 | 37 | 78.7 | ||
>6.9 KU/l | 59 | 40 | 67.8 | 19 | 32.2 | ||
Lymphatic node metastasis | 9.133 | 0.003 | |||||
No | 60 | 36 | 60.0 | 24 | 40.0 | ||
Yes | 46 | 14 | 30.4 | 32 | 69.6 | ||
TNM stage | 15.222 | <0.001 | |||||
I and II | 27 | 4 | 14.8 | 23 | 85.2 | ||
III | 41 | 24 | 58.5 | 17 | 41.5 | ||
IV | 38 | 22 | 57.9 | 16 | 42.1 | ||
Tumor stage | 13.151 | 0.001 | |||||
T1-T2 | 28 | 5 | 17.9 | 23 | 82.1 | ||
T3 | 44 | 25 | 56.8 | 19 | 43.2 | ||
T4 | 34 | 20 | 58.8 | 14 | 41.2 |
TNFAIP8, tumor necrosis factor-α-induced protein 8; TNM, TNM Classification of Malignant Tumours; CA72-4, carbohydrate antigen 72-4.