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. 2016 May 10;12(1):238–244. doi: 10.3892/etm.2016.3327

Table I.

Correlation of TNFAIP8 expression with clinical and pathological characteristics of gastric adenocarcinoma patients.

TNFAIP8 expression

Cases Positive Negative


Variable n n % n % χ2 P-value
Total cases 106 50 47.2 56 52.8
Gender 1.500 0.221
  Male 70 36 51.4 34 48.6
  Female 36 14 38.9 22 61.1
Age (years)
  ≥60 74 34 45.9 40 54.1 0.147 0.701
  <60 32 16 50.0 16 50.0
Pathological grading 4.413 0.110
  Well differentiated 14 3 21.4 11 78.6
  Moderately differentiated 24 13 54.2 11 45.8
  Poorly differentiated 68 34 50.0 34 50.0
Tumor size (maximum diameter) 0.482 0.488
  ≤5.0 cm 31 14 45.2 17 54.8
  >5.0 cm 75 37 49.3 38 51.7
Vascular invasion 9.974 0.002
  Yes 66 39 59.1 27 40.9
  No 40 11 27.5 29 72.5
CA72-4 22.718 <0.001
  ≤6.9 KU/l 47 10 21.2 37 78.7
  >6.9 KU/l 59 40 67.8 19 32.2
Lymphatic node metastasis 9.133 0.003
  No 60 36 60.0 24 40.0
  Yes 46 14 30.4 32 69.6
TNM stage 15.222 <0.001
  I and II 27 4 14.8 23 85.2
  III 41 24 58.5 17 41.5
  IV 38 22 57.9 16 42.1
Tumor stage 13.151 0.001
  T1-T2 28 5 17.9 23 82.1
  T3 44 25 56.8 19 43.2
  T4 34 20 58.8 14 41.2

TNFAIP8, tumor necrosis factor-α-induced protein 8; TNM, TNM Classification of Malignant Tumours; CA72-4, carbohydrate antigen 72-4.