Fig. 2.

Conserved synteny of the chromosomal blocks carrying the PDE6 catalytic subunit genes resulting from 2R. The figure illustrate the identified chromosomal regions harbouring the PDE6 catalytic subunit gene family and the neighbouring gene families in human, chicken, spotted gar and zebrafish. The presence of a quartet of regions in human, chicken and spotted gar is consistent with 2R expansion resulting in a paralogon. In the zebrafish the chromosomal regions are rearranged which is consistent with chromosomal rearrangements after 3R in the teleost lineage. The families are shown in alphabetical order and each of the boxes are coloured after the chromosomal location of their human ortholog. The numbers under the boxes are the genomic locations in mega base pairs unless otherwise stated