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. 2016 Jun 1;12(1):413–420. doi: 10.3892/ol.2016.4659

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Figure 3. — Prx1 knockout increases cell apoptosis in tongue precancerous lesions. (A) Terminal deoxynucleotidyl transferase dUTP nick-end labeling assay in (a) wild-type control group, (b) wild-type 4NQO group, (c) wild-type 4NQO + H₂O₂ group, (d) Prx1 knockout control group, (e) Prx1 knockout 4NQO group and (f) Prx1 knockout 4NQO + H₂O₂ group (magnification, ×400). (B) Prx1 negatively regulated the apoptotic rate of cells in mouse tongue premalignant lesions. *0.01<P<0.05; **0.000<P<0.01; ***P=0.000. Prx1, peroxiredoxin 1; 4NQO, 4-nitroquinoline-1-oxide.