Figure 1.

The reactome pathway diagram, demonstrating the primary signaling and functional molecular pathways of the complement system on a target cell. In this diagram, multiple activation pathways are shown, eventually effecting cell lysis and breakdown of the target cell. This also shows secondary signaling pathways for C3a signaling for pro-inflammation and cytokine activity with C5a-promoting chemotaxic recruitment of inflammatory cells. Retrieved from: http://www.reactome.org/figures/Pathway_Illustrations/Complement_Cascade_72_oicr.png; reused under the Creative Commons license.