Table 5.
Effects of each treatment on TXB2, 6-keto-PGF1α and the TXB2/6-keto-PGF1a ratio in k-carrageenan-induced rat tail thrombosis model (n = 10)
| Groups | TXB2 | 6-keto-PGFlα | TXB2/6-keto-PGFlα |
|---|---|---|---|
| Control | 498 ± 32## | 889 ± 28## | 0.56 ± 0.04## |
| Model | 696 ± 39 | 586 ± 24 | 1.19 ± 0.08 |
| CMC-Na | 703 ± 37 | 550 ± 22## | 1.28 ± 0.08## |
| Aspirin | 658 ± 44* | 741 ± 23** | 0.89 ± 0.06** |
| Eugenol | 678 ± 58 | 699 ± 30** | 0.97 ± 0.09** |
| AEE L | 605 ± 22** | 667 ± 17** | 0.91 ± 0.04** |
| AEE M | 612 ± 45** | 737 ± 13** | 0.83 ± 0.07** |
| AEE H | 644 ± 23** | 599 ± 26** | 1.08 ± 0.07** |
| Combination | 598 ± 51** | 701 ± 31** | 0.86 ± 0.10** |
Blood samples anticoagulated with EDTA-K2 were centrifuged at 1000 g for 10 min to obtain plasma, which was analyzed using ELISA kits. Data are expressed as mean ± SD. ## P < 0.01 compared with the model group. *P < 0.05, **P < 0.01 compared with the CMC-Na group. AEE L: AEE 18 mg/kg; AEE M: 36 mg/kg; AEE H: AEE 72 mg/kg; Combination: combination of aspirin and eugenol (molar ratio 1:1)