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Mice constitutively lacking EC Map4k4 develop chylothorax. (A) Map4k4 (M4K4) Cdh5 Cre animals die at a median of p8.5 (n = 26; P < 0.0001). (B) Map4k4 Cdh5 Cre animal at p7 displaying chylothorax. (C) Fluid from the thoracic cavity of a representative Map4k4 Cdh5 Cre animal.
