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Effect of encapsulation on virulence in the juvenile rat intraperitoneal infection model. Shown are Kaplan-Meyer survival curves for groups of eight 5-day-old Sprague-Dawley rats injected via the intraperitoneal route with 100 μl of PBS or 7.5 × 107 CFU of the KK01, ctrA, csaA, or csaA(csaA) strain in 100 μl PBS. The PBS control and the ctrA mutant have overlapping survival curves with 100% survival.
