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Downregulation of SENP1 induced apoptosis in human glioma cells. (A) Flow cytometry was used to detect the apoptosis of LN-299 cells. (B) Downregulation of SENP1 increased the apoptosis rate of human glioma cells. **P<0.01. SENP1, small ubiquitin-related modifier protein-specific protease 1; shRNA, short hairpin RNA; FITC, fluorescein isothiocyanate; PI, propidium iodide; Control shRNA, pGenesil-1 scramble control group; SENP1 shRNA, pGenesil-1-SENP1 transfected group.
