FIG 5.

Plasma cytokine analysis. (A) Plasma was collected 24 h after the final IFN-α injection in both the acute- and established-infection experiments and assayed for human cytokine and chemokine levels using a custom 11-plex bead assay. Data from 11 days postinfection are shown. (B) Comparison of CXCL10 levels in plasma collected from mice at 11 dpi (one-way ANOVA with Dunnet's posttest; *, P < 0.05) or 45 dpi (unpaired t test; *, P < 0.05). Analyte levels were quantified in picograms per milliliter of TKO-BLT plasma using standards provided with the assay. Each dot represents a separate mouse.