TABLE 2.
Differentially expressed genes in E7-expressing cells
| Gene designation | Ratio of E7/vector by RNA-seq | Regulation categorya (reference[s]) | Product description |
|---|---|---|---|
| S100P | 4.27 | ↑ (50, 52) | S100 calcium binding protein P |
| DHFR | 3.54 | ↑ (53) | Dihydrofolate reductase |
| CDC6 | 3.00 | ↑ (54) | Cell division cycle 6 |
| RAD51AP1 | 1.98 | ↑ (55) | RAD51-associated protein 1 |
| APOBEC3B | 1.97 | ↑ (47) | Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B |
| DEK | 1.80 | ↑ (48, 49) | DEK oncogene |
| CDC25A | 1.82 | ↑ (56) | Cell division cycle 25A |
| MSH6 | 1.78 | ↑ (57) | MutS homolog 6 |
| CCNA2 | 1.78 | ↑ (57) | Cyclin A2 |
| BARD1 | 1.77 | ↑ (59) | BRCA1-associated RING domain 1 |
| MYBL2 | 1.79 | ↑ (7, 46) | V-myb myeloblastosis viral oncogene homolog (avian)-like 2 |
| S100A8 | 1.70 | ↑ (58) | S100 calcium binding protein A8 |
| FN1 | 0.50 | ↓ (59) | Fibronectin 1 |
a
Upward-pointing arrows represent upregulation; downward-pointing arrows represent downregulation.