Table I.
Ratio (SPOP/CEP17) | Status of SPOP gene | Status of CEP17 | Ovarian cancer tissue, n | Normal ovarian tissue, n |
---|---|---|---|---|
Total | 88 | 10 | ||
Ratio >2 | Amplification | – | 1 | 0 |
0.7≤ratio≤2; CEP17<1.5 | – | Monosomy | 45 | 0 |
0.7≤ratio≤2; 1.5≤CEP17≤2.5 | – | Disome | 37 | 10 |
0.7≤ratio≤2; CEP17 >2.5 | – | Polysomy | 4 | 0 |
Ratio <0.7 | Deletion | – | 1 | 0 |
SPOP/CEP17, fluorescence in situ hybridization ratio of speckle-type POZ (pox virus and zinc finger protein) protein to chromosome enumeration probe 17.