Fig. 1.

Genome-wide CNA profile of melanoma samples. (a) LRR and BAF calls from WES of matched normal and tumor samples. (b) Bivariate genome-wide allele-specific copy number profile (detailed in Supplementary Materials) and nonparametric Bayesian clustering based on Chinese Restaurant Process (CRP). (c) Predicted copy number status. (d) Density estimation of minor allele copy number estimation by the Dirichlet Process mixture of normal distributions. (e) Hierarchical clustering of 253 melonoma samples based on the minor allele copy number estimates