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. 2015 Dec 31;32(9):1308–1315. doi: 10.1093/bioinformatics/btv749

Table 1.

SPMM estimates

Subject ID K Days post infection with 95% CI P # SSE
Heterosexual
SC33 2 22.4 [14.8–30.1] 0.040 0.0049 (1053.2)
TT27P 3 10.8 [6.4–15.2] 0.33 0.0020 (1538.3)
CAP8a 2 (1) 49.1 [35.4–62.9] 0.18 0.0032 (612.6)
CAP224 2 20.2 [11.7–28.8] 0.57 0.0091 (510.7)
703010228 2 21.3 [13.9–28.7] 0.89 0.0010 (1040.4)
SC31a 2 (1) 24.2 [17.4–31.1] 0.095 0.019 (2104.2)
CAP222a 4 (3) 14.0 [7.2–20.8] 0.071 0.0063 (564.9)
0478a 2 (3) 54.2 [40.3–68.2] 0.021 0.011 (721.7)
703010010 3 11.9 [5.8–18.0] <0.0001 0.039 (631.0)
CAP136 2 36.7 [23.2–50.2] 0.33 0.0085 (327.1)
CAP260 2 28.3 [14.9–41.7] 0.45 0.018 (186.1)
Z30 2 64.0 [50.2–77.9] 0.15 0.0062 (1040.1)
CAP37 3 46.1 [33.3–58.9] 0.55 0.024 (839.6)
0114 3 32.3 [22.5–42.0] 0.82 0.0012 (861.7)
703010200a 4 (3) 42.0 [28.6–54.6] 0.89 0.013 (497.5)
1335 3 28.4 [18.4–38.4] 0.32 0.012 (617.8)
706010151a 3 (2) 49.2 [31.8–66.6] 0.044 0.023 (257.5)
CAP69a 7 (5) 4.8 [0.095–9.41] 0.85 0.0074 (205.4)
1196 3 49.5 [36.9–62.1] 0.40 0.017 (884.2)
MSM
Z35 2 19.3 [11.1–27.5] 0.20 0.050 (571.9)
CAAN5342a 2 (>2) 30.2 [22.0–38.5] 0.49 0.017 (1547.5)
Z16a 4 (5) 65.7 [49.4–82.0] 0.97 0.0038 (575.9)
BORI0637 5 17.2 [10.1–24.3] 0.84 0.0055 (698.3)
Z18a 4 (3) 33.2 [24.2–42.2] 0.039 0.024 (1425.1)
Z03a 2 (3) 102.3 [83.1–121.6] 0.39 0.034 (859.9)
IDU
HDNDRPI029a 2 (1) 56.0 [44.5–67.6] <0.0001 0.012 (1820.7)
HDNDRPI032 3 53.4 [39.6–67.2] 0.87 0.0098 (682.2)
HTM319a 8 (3) 50.1 [36.4–63.9] 0.00019 0.0047 (662.7)
PSL024 4 50.5 [33.5–67.5] <0.0001 0.029 (303.5)
HDNDRPI001a 4 (5) 67.3 [49.6–84.9] 0.0047 0.0090 (480.4)
I034-3 8 123.2 [113.6–132.7] <0.0001 0.014 (28068.0)
700010019a 6 (>3) 15.0 [7.3–22. 7] 0.62 0.018 (417.5)
HDNDRPI034a 9 (16) 30.0 [23.6–36.3] 0.08 0.0064 (4163.5)
Risk g roup u nknown
9076-08 2 13.5 [8.1–18.9] 0.74 0.0040 (1153.4)
62615-03 3 9.3 [4.6–14.0] 0.36 0.0042 (809.7)
9026-07 2 14.0 [6.0–22.0] 0.97 0.011 (275.1)
12008-09 2 8.0 [3.5–12.5] 0.61 0.0079 (751.7)
PRB957-06a 3 (4) 52.5 [42.0–63.0] <0.0001 0.047 (2355.0)
63068-05 2 13.3 [6.3–20.2] 0.34 0.030 (441.8)
701010016 2 49.4 [35.6–63.2] 0.14 0.0095 (622.2)
1051-12a 3 (4) 29.9 [23.5–36.4] <0.0001 0.015 (4530.4)

aSubjects who were estimated to have a different number of founder strains using phylogenetic methods (Previously-published, phylogenetic tree-based estimates for the number of founder viruses are presented in parenthesis).

#Less than 0.05 implies statistically significant deviation from the SPMM.