Table 1.

Association Between Baseline Human Papillomavirus (HPV) Serum Antibody Level and Risk of Incident Type-Specific Oral HPV Infection Among Men Participating in the HPV Infection in Men Study

Serostatus at Baseline	Any HPV Typea			HPV-6		HPV-16
	Infections, No.	Univariate HR (95% CI)	Multivariableb aHR (95% CI)	Infections, No.	Univariate HR (95% CI)	Infections, No.	Univariate HR (95% CI)
Seronegative	21	1.00	1.00	6	1.00	14	1.00
Seropositivec	4	1.63 (.56–4.76)	1.51 (.49–4.69)	1	1.78 (.21–14.78)	3	1.70 (.49–5.90)
Antibody titer, log10	25	1.81 (.57–5.74)	1.66 (.52–5.23)	7	3.02 (.43–21.25)	17	1.29 (.30–5.62)

All analyses are HPV type specific. Participants were recruited in Tampa, Florida, Cuernavaca, Mexico, and São Paulo, Brazil.

Abbreviations: aHR, adjusted hazard ratio; CI, confidence interval; HR, hazard ratio.

^a Defined as HPV-6, −11, −16, and −18.

^b Adjusted for lifetime number of sex partners (female and male).

^c Defined as ≥0.2, ≥0.3, ≥0.2, and ≥0.2 OD units for HPV-6, -11, -16, and -18, respectively.