Table 1.
Characteristics | CPFE group (n=11) | Emphysema group (n=108) | IP group (n=7) | Normal group (n=124) | P-value |
---|---|---|---|---|---|
Sex (M/F) | 11 (100%)/0 | 96 (88.9%)/12 | 5 (71.4%)/2 | 62 (50%)/62 | <0.0001 |
Age (year) | 72.4±10.3 | 70.8±7.1 | 71.7±6.1 | 69.8±8.2 | ns |
BMI (kg/m2) | 23.1±3.8 | 22.1±3.1 | 20.1±2.3 | 22.4±3.7 | ns |
Smoking index (pack-year) | 46.8±31.7a | 57.5±31.3a | 37.9±36.6 | 20.4±30.1 | |
Pulmonary function tests | |||||
FVC | 2.90±0.69 | 3.30±0.67a | 2.65±0.73 | 2.90±0.71 | |
%FVC | 93.7±18.4 | 103.8±16.1 | 91.5±20.5 | 105.5±19.7 | ns |
FEV1.0 | 2.05±0.51 | 3.58±10.67 | 2.04±0.40 | 2.15±0.54 | ns |
%FEV1.0 | 87.8±22.7a | 92.1±22.1a | 95.1±18.7 | 109.9±22.2 | |
FEV1.0/FVC | 71.2±9.8b | 65.5±11.0a,b | 86.8±30.1a,c | 74.5±8.8b,c | |
%DLCO | 71.3±20.8a | 84.3±24.0a | 99.9±39.6 | 108.2±27.0c | |
%DLCO/VA | 69.2±19.7a | 70.5±20.8a,b | 88.8±22.4c | 94.4±18.2c | |
PaO2 | 92.8±23.7 | 83.1±12.6 | 86.3±9.9 | 87.9±13.3 | ns |
PaCO2 | 38.1±5.1 | 39.1±3.9 | 40.9±3.8 | 39.0±3.1 | ns |
Notes: Data are presented as mean ± SD.
P<0.05 for Tukey–Kramer test with data from normal group.
P<0.05 for Tukey–Kramer test with data from IP group.
P<0.05 for Tukey–Kramer test with data from emphysema group.
Abbreviations: CPFE, combined pulmonary fibrosis and emphysema; IP, interstitial pneumonia; M, male; F, female; BMI, body mass index; %FVC, percentage of forced vital capacity; FEV1.0, forced expiratory volume in 1 second; %DLCO, percentage of diffusion capacity of the lung for carbon monoxide; VA, alveolar volume; PaO2, partial pressure of arterial oxygen; PaCO2, partial pressure of arterial carbon dioxide; SD, standard deviation; ns, not significant.