Table 5.
Univariate analysis of prognostic factors using Cox proportional hazard model
| Variable | Hazard ratio | 95% CI | 95% CI | P-value |
|---|---|---|---|---|
| Age | 1.054804 | 1.000 | 1.0007 | 0.002 |
| Sex | ||||
| Female | Reference | |||
| Male | 2.830 | 1.452 | 6.203 | 0.0015 |
| BMI | 0.965 | 0.893 | 1.038 | 0.350 |
| Smoking index | 1.000 | 1.000 | 1.000 | 0.010 |
| Pulmonary function data | ||||
| %FVC | 0.979 | 0.969 | 0.990 | 0.0007 |
| %FEV1.0 | 0.993 | 0.982 | 1.004 | 0.263 |
| FEV1.0/FVC | 1.007 | 0.984 | 1.029 | 0.511 |
| %DLCO | 0.982 | 0.969 | 0.994 | 0.004 |
| %DLCO/VA | 0.983 | 0.968 | 0.997 | 0.023 |
| Type of procedure | ||||
| Segmentectomy/partial resection | Reference | |||
| Lobectomy | 1.441 | 0.716 | 3.309 | 0.322 |
| Pneumonectomy | 4.200 | 1.265 | 12.634 | 0.021 |
| Pathological stage | ||||
| I | Reference | |||
| II | 2.498 | 1.209 | 4.878 | 0.014 |
| III | 3.829 | 1.974 | 7.167 | 0.0002 |
| IV | 2.087 | 0.336 | 6.979 | 0.365 |
| Group | ||||
| Normal | Reference | |||
| CPFE | 6.147 | 2.515 | 13.730 | 0.0002 |
| Emphysema | 2.021 | 1.126 | 3.720 | 0.018 |
| IP | 2.843 | 0.665 | 8.425 | 0.139 |
Abbreviations: CI, confidence interval; BMI, body mass index; %FVC, percentage of forced vital capacity; FEV1.0, forced expiratory volume in 1 second; %DLCO, percentage of diffusion capacity of the lung for carbon monoxide; VA, alveolar volume; CPFE, combined pulmonary fibrosis and emphysema; IP, interstitial pneumonia.