Table 6.
Multivariate analysis of prognostic factors using Cox proportional hazard model
| Variable | Hazard ratio | 95% CI | 95% CI | P-value |
|---|---|---|---|---|
| Age | 1.087 | 1.022 | 1.16 | 0.007 |
| Sex | ||||
| Female | Reference | |||
| Male | 2.495 | 0.720 | 12.26 | 0.160 |
| Smoking index | 1.000 | 0.999 | 1.000 | 0.305 |
| Pulmonary function data | ||||
| %FVC | 0.968 | 0.946 | 0.99 | 0.006 |
| %DLCO | 0.989 | 0.966 | 1.012 | 0.377 |
| %DLCO/VA | 0.995 | 0.966 | 1.026 | 0.791 |
| Type of procedure | ||||
| Segmentectomy/partial resection | Reference | |||
| Lobectomy | 2.731 | 0.857 | 10.24 | 0.091 |
| Pneumonectomy | 3.656 | 0.612 | 21.89 | 0.152 |
| Pathological stage | ||||
| I | Reference | |||
| II | 2.288 | 0.766 | 6.302 | 0.132 |
| III | 3.370 | 1.308 | 8.510 | 0.012 |
| IV | 36.35 | 4.241 | 234.6 | 0.002 |
| Group | ||||
| Normal | Reference | |||
| CPFE | 8.004 | 1.712 | 34.62 | 0.009 |
| Emphysema | 1.562 | 0.635 | 4.146 | 0.337 |
| IP | 5.996 | 1.079 | 27.79 | 0.041 |
Abbreviations: CI, confidence interval; %FVC, percentage of forced vital capacity; %DLCO, percentage of diffusion capacity of the lung for carbon monoxide; VA, alveolar volume; CPFE, combined pulmonary fibrosis and emphysema; IP, interstitial pneumonia.