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. 2016 Jun 9;11:1139–1150. doi: 10.2147/COPD.S103873

Table 5.

Asthma history differences between patients with asthma only and ACOS

Variable ACOS (N=366) Asthma only (N=825) P-value
Years diagnosed (asthma) 0.039
 n 312 667
 Mean ± SD 11.5±12.6 9.9±10.7
Diagnosing physician (asthma) 0.129
 General internist (%) 154 (42.08) 285 (34.55)
 Allergist (%) 46 (12.57) 105 (12.73)
 Pediatrician (%) 18 (4.92) 43 (5.21)
 Pulmonologist (%) 87 (23.77) 199 (24.12)
 Other (%) 7 (1.91) 35 (4.24)
Asthma severity (with medication) 0.164
 Mild intermittent (%) 188 (51.37) 395 (47.88)
 Mild persistent (%) 79 (21.58) 161 (19.52)
 Moderate persistent (%) 19 (5.19) 59 (7.15)
 Severe persistent (%) 2 (0.55) 2 (0.24)
Asthma severity (without medication) <0.001
 Mild intermittent (%) 152 (41.53) 362 (43.88)
 Mild persistent (%) 109 (29.78) 274 (33.21)
 Moderate persistent (%) 89 (24.32) 163 (19.76)
 Severe persistent (%) 16 (4.37) 26 (3.15)
Asthma treatment <0.001
 Untreated (%) 33 (9.02) 71 (8.61)
 OTC only (%) 95 (25.96) 211 (25.58)
 Rx only (%) 88 (24.04) 209 (25.33)
 OTC and Rx (%) 150 (40.98) 334 (40.48)
Causes of asthma
Allergies/allergic reaction (%) 190 (51.91) 373 (45.21) 0.013
Exercise/physical activity (%) 69 (18.85) 176 (21.33) 0.485
Illnesses/conditions (eg, colds, flu) (%) 188 (51.37) 334 (40.48) 0.003
Pollutants/airborne irritants (%) 156 (42.62) 296 (35.88) <0.001
Secondhand smoke (%) 82 (22.40) 153 (18.55) 0.149
Stress/anxiety/emotional states (%) 97 (26.50) 168 (20.36) 0.036
Weather/temperature (%) 166 (45.36) 290 (35.15) 0.010
None of these (%) 3 (0.82) 16 (1.94) <0.001
ACT score <0.001
 N 366 825
 Mean ± SD 18.8±4.6 18.3±4.7

Note: The P-values in this table are based on a chi-square test (for categorical variables) or a one-way ANOVA test (for continuous variables).

Abbreviations: ACT, asthma control test; ACOS, asthma COPD overlap syndrome; COPD, chronic obstructive pulmonary disease; OTC, over-the-counter; SD, standard deviation; Rx, prescription medication.