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. 2016 Jun 9;11:1245–1259. doi: 10.2147/COPD.S101003

Table S1.

Patient baseline characteristics and clinical outcome with respect to baseline TL perfusion

Parameters Below median TL perfusion (<8.11%) Above median TL perfusion (≥8.11%) P-value
N 27 27
Baseline TL perfusion 4.8±1.7 11.9±2.7 0.001
Sex, n, (male/female) 14/13 17/10 ns
Age (yr) 69.8±5.7 66.6±5.0 0.027
BMI (kg/m2) 25.1±5.1 25.5±4.8 ns
Smoking history (pack-yr) 42.3±15.9 53.6±24.0 ns
HI <12.2% 11 14 ns
HI ≥12.2% 14 12
Treatment site 0.001
 RUL 2 5
 RLL 0 4
 LUL 2 11
 LLL 23 7
Baseline FEV1 (% pred) 27.4±6.5 25.8 ±7.3 ns
Baseline VC (% pred) 65.3±11.9 63.6±14.7 ns
Baseline RV (% pred) 217±40 217±36 ns
Baseline TLC (% pred) 123±17 120±11 ns
Baseline KCO (% pred) 43.4±23.0 28.9±13.9 0.042
Baseline 6MWT (m) 239±80 212±98 ns
Baseline SGRQ (points) 63.0±12.4 66.7±13.0 ns
ΔFEV1 (%) 19.8±22.4 27.3±26.8 ns
ΔVC (%) 14.1±23.2 15.2±20.0 ns
ΔRV (%) −9.8±17.9 −5.6±17.4 ns
ΔTLC (%) −3.2±11.2 −0.04±8.6 ns
ΔKCO (%) 17.4±52.6 42.1±57.8 ns
Δ6MWT (m) 26.4±47.2 38.8±76.0 ns
ΔSGRQ (points) −7.1±13.8 −11.9±13.8 ns

Notes: Data are presented as mean ± standard deviation. P-values were calculated for categorical variables using the chi-square test and Fisher’s exact test, and for continuous variables using the Mann–Whitney U-test.

Abbreviations: TL perfusion, baseline percentage perfusion of TL; TL, target lobe; ns, not significant; BMI, body mass index; HI, heterogeneity index; RUL, right upper lobe; RLL, right lower lobe; LUL, left upper lobe; LLL, left lower lobe; FEV1, forced expiratory volume in 1 second; VC, vital capacity; RV, residual volume; TLC, total lung capacity; KCO, diffusing capacity of the lung for carbon monoxide; SGRQ, St George’s Respiratory Questionnaire; 6MWT, 6-minute walk test distance; Δ, change from baseline to follow-up.