Table 1. Summaries of the studies included.
| Author | Design | Population characteristics | Country | Male/female | Age (years) | BMI | Cut-off (Kpa) | Liver biopsy for fibrosis staging | Manufacturers of the instrument for SWE |
|---|---|---|---|---|---|---|---|---|---|
| Ferraioli G et al.2012 | Prospective cohort study | Patients with chronic hepatitis C | Italy | 87/34 | 44.8±11.9 | 25.4±3.8 | ≥F2:7.1;≥F3:8.7;F4:10.4 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Leung VY et al.2013 | Prospective cohort study | Patients with chronic hepatitis B | China | 214/183 | 48.8±12.3 | 24.2±18.6 | ≥F1:6.5;≥F2:7.1;≥F3:7.9;F4:10.1 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Cassinotto C et al.2014 | Prospective cohort study | Patients with 8 hepatitis C;33 hepatitis B;145 non-alcoholic steatohepatitis;8 viral reactivation post-liver transplantation;5 sclerosing cholangitis;16 autoimmune diseases;7 hepatitis E;7 primary biliary cirrhosis;13 drug-related hepatitis;3 hemochromatosis;2 overlap syndrome;31 unexplained chronic cytolysis | France | 188/161 | 54.8±14 | 27.4±6.4 | ≥F1:7.8;≥F2:8;≥F3:8.9;F4:10.7 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Zeng J et al.2014 | Prospective cohort study | Patients with chronic hepatitis B | China | a)169/37;b)82/22 | a)36.3±9.4;b)37.2±10.9 | a)22.3±3.2;b)22.1±3.4 | ≥F2:7.2;≥F3:9.1;F4:11.7 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Beland M et al.2014 | Prospective cohort study | Patients with 21 hepatitis C;15 elevated liver function tests;5 nonalcoholic steatohepatitis;3 cirrhosis;3 autoimmune hepatitis;2 hepatitis B;1 methotrexate therapy | USA | 25/25 | 52 | NA | ≥F2:10.49 (1.87m/s), using the conversion formula from kPa to m/s as √(kPa/3) | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Suh CH et al.2014 | Retrospective cohort study | Patients with 123 nonsteatotic;73 hepatic steatosis | Korea | 130/66 | 29.2±9.2 | 22.8±3.0 | ≥F1:6.2 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Deffieux T et al.2015 | Prospective cohort study | Patients with 44 hepatitis C;24 hepatitis B;11 healthy liver;11 non-alcoholic steatohepatitis;10 alcoholic liver;10 autoimmune diseases;2 hepatitis E;2 primary biliary cirrhosis;2 cryptogenic cirrhosis;2 steatosis;1 drug-related hepatitis;1 hepatocellular carcinoma | France | 86/34 | 46.2±14.3 | 24.2±4.09 | ≥F2:8.9;≥F3:9.1;F4:10.2 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Zheng J et al.2015 | Prospective cohort study | Patients with 9 hepatitis C;164 hepatitis B;7 alcoholic liver;3 autoimmune diseases;4 primary biliary cirrhosis;4 drug-related hepatitis;7 unclassified | China | 119/48 | Male:36.6±9.7;female:39.7±11.8 | 21.6±3.4 | NA | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Tada T et al.2015 | Retrospective cohort study | Patients with hepatitis C | Japan | 23/32 | 61 | 21.3 | ≥F2:8.8 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Samir AE et al.2015 | Prospective cohort study | Patients with 43 hepatitis C;8 hepatitis B;1 alcoholic liver;18 autoimmune diseases;1 hemochromatosis;1 HIV and HCV coinfection;60 elevated liver function test;4 elevated liver function test after transplantation; | USA | 70/66 | 49 | NA | ≥F2:7.29;≥F3:8.90;F4:9.59 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Yoneda M et al.2015 | Prospective cohort study | Patients with 117 hepatitis C;15 hepatitis B;7 alcoholic liver;13 non-alcoholic steatohepatitis;4 autoimmune diseases;6 primary biliary cirrhosis;9 primary sclerosing cholangitis;5 others | USA | 115/59 | 57±12 | 30.1±4.1 | a)≥F1:6.2;≥F2:7.9;≥F3:9.3;F4:11.4;b)≥F1:7.4;≥F2:8.6;≥F3:10.9;F4:14.7 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Guibal A et al.2016 | Prospective cohort study | Patients with 30 non-alcoholic steatohepatitis;22 hepatitis B or C;17 alcoholic liver;4 autoimmune hepatitis;4 chronic biliary disease;14 others | France | 95/53 | 54.3±13.2 | 24.9±4.3 | ≥F2:8.8;≥F3:11.5;F4:18.1 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
| Verlinden W et al.2016 | Retrospective cohort study | Patients with 80 hepatitis C, including 26 coinfected with HIV | Belgium | 63/17 | 43±10.2 | NA | ≥F2:8.5;≥F3:10.4;F4:11.3 | METAVIR | Aixplorer,SuperSonic Imagine,Aix-en-Provence,France |
NA:not available