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. 2016 Jun 14;11(6):e0157409. doi: 10.1371/journal.pone.0157409

Fig 1. Structures of mature10E8 antibody and its genomic revertants.

Fig 1

(A) (left) Mature antibody-MPER complex (PDB ID: 4G6F). The MPER peptide is colored red and the mature 10E8 antibody heavy chain in pink and light chain in gray. (right) The ligand-free 10E8 Fab is structurally aligned to the 10E8-MPER complex structure with an overall Cα r.m.s.d of 0.2 Å. (B) (left) Ligand-free structures of germline-reverted gHv/gLv and (right) partially reverted gHv/mature L structurally aligned to the mature 10E8 with an overall Cα r.m.s.d of 0.2 Å. Structural differences with Cα r.m.s.d. greater than 2.0 Å are colored in red and displayed in stick representation.