. 2016 Jun 14;11(6):e0157079. doi: 10.1371/journal.pone.0157079

Table 3. Ubr5 is required for embryonic mid-gestational viability—E13.5 analysis.

Genotype	Expected Frequency (%)	Observed Frequency (%)
Ubr5^+/+	12.5	20 (n = 7)
Ubr5^+/+; CreER^T2	12.5	29 (n = 10)
Ubr5^+/WT*	25	20 (n = 7)
*Ubr5^+/mt; CreER^T2**	25	3 (n = 1)
Ubr5^WT/WT	12.5	29 (n = 10)
*Ubr5^mt/mt; CreER^T2*	12.5	0 (n = 0)

Ubr5 function is required for mid-gestation viability. Pregnant females were injected i.p with tamoxifen at E11.5 and embryos genotyped at E13.5 (Table 3) and E15.5 (Table 2). Chi squared analysis: E15.5 = p 0.0179 and E13.5 = p = 0.0001.