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. 2016 Jun 8;11:2685–2694. doi: 10.2147/IJN.S106297

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© 2016 Abbasi et al. This work is published and licensed by Dove Medical Press Limited

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Elimination of the biphasic pharmacodynamics of free 15d-PGJ2 by SRNE.

Notes: RAW264.7 cells were incubated with free 15d-PGJ2 and 15d-PGJ2-loaded SRNE and FRNE for 24 hours before the WST-8 assay. Data represent the mean ± SD (n=3).

Abbreviations: 15d-PGJ2, 15-deoxy-Δ12,14-prostaglandin J2; FRNE, fast-release NE; NE, nanoemulsion; NT, nontreated; SRNE, slow-release NE; WST-8, water-soluble tetrazolium salt.