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A proposed mechanism for the elimination of the biphasic pharmacodynamics of 15d-PGJ2 by SRNE and the specific induction of apoptosis.
Abbreviations: 15d-PGJ2, 15-deoxy-Δ12,14-prostaglandin J2; DP2, prostaglandin D2 receptor 2; FRNE, fast-release NE; NE, nanoemulsion; NF-κB, nuclear factor-κB; PPARγ, peroxisome proliferator-activated receptor γ; SRNE, slow-release NE.
