Table 1.
The effect of components and their amounts on NE properties
| NE | Composition (µmol)
|
Characteristics
|
||||||
|---|---|---|---|---|---|---|---|---|
| Triolein | DSPC | Tween 80 | 15d-PGJ2 | Size (nm) | PDI | ζ-potential (mV) | Encapsulation % | |
| 1 | 21 | 9 | 0 | 0.5 | 131±12 | 0.20±0.01 | −4.8±1.0 | 83±7 |
| 2 | 21 | 9 | 1 | 0.5 | 100±1 | 0.24±0.01 | −5.2±0.3 | 84±5 |
| 3 | 21 | 9 | 4 | 0.5 | 59±1 | 0.25±0.00 | −7.4±0.4 | 90±6 |
| 4 | 21 | 9 | 12 | 0.5 | 37±4 | 0.20±0.04 | −7.9±0.9 | 94±4 |
| 5 | 21 | 3 | 12 | 0.5 | 53±3 | 0.19±0.01 | −10.5±1.0 | 97±4 |
| 6 | 21 | 1 | 12 | 0.5 | 72±4 | 0.22±0.01 | −12.1±1.0 | 94±4 |
| 7 | 28 | 9 | 12 | 0.5 | 56±5 | 0.22±0.02 | −8.8±1.5 | 97±1 |
| 8 | 35 | 9 | 12 | 0.5 | 93±5 | 0.23±0.01 | −9.4±0.1 | 99±0 |
| 9 | 14 | 6 | 8 | 0.5 | 33±1 | 0.16±0.02 | −10.8±1.7 | 93±2 |
| 10 | 7 | 3 | 4 | 0.5 | 32±3 | 0.14±0.04 | −9.2±1.3 | 88±3 |
Note: Data are presented as mean ± SD (n=3).
Abbreviations: 15d-PGJ2, 15-deoxy-Δ12,14-prostaglandin J2; DSPC, 1,2-distearoyl-sn-glycero-3 phosphocholine; NE, nanoemulsion; PDI, polydispersity index.