Table 2.
Biochemical parameters of PPT-treated animals
Groups | WBC (1012/L) | RBC (109/L) | LYMPH (109/L) | ALT (mmol/L) | AST (mmol/L) | BUN (mmol/L) | CRE (mmol/L) |
---|---|---|---|---|---|---|---|
Control | 10.062±0.64 | 10.825±0.61 | 95.19±1.56 | 183.3±73.83 | 39.40±10.25 | 10.751±1.20 | 33.00±6.20 |
PP | 9.843±3.47 | 10.62±0.32 | 96.34±3.47 | 194.32±46.23 | 47.45±16.43 | 12.43±2.01 | 32.67±6.32 |
PPT | 11.07±1.86 | 11.26±0.35 | 95.44±2.06 | 207.00±52.72 | 57.60±21.46 | 11.784±1.33 | 29.90±2.92 |
TP | 8.03±2.34* | 10.39±0.47 | 87.54±2.24*** | 338.00±63.01*** | 142.14±18.07*** | 15.87±3.06*** | 38.86±3.34* |
Notes:
P<0.05,
P<0.001 vs control group. Data presented as mean ± standard deviation.
Abbreviations: PP, l-PAE-γ-PGAcomplex; γ-PGA, poly-γ-glutamic acid; l-PAE, l-phenylalanine ethylester; PPT, γ-PGA-l-PAE-TP; TP, triptolide; WBC, white blood cell; RBC, red blood cell; LYMPH, lymphocyte; ALT, serum alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CRE, creatinine.