Table 1.
Baseline characteristicsa of participants according to race and quintiles of parathyroid hormoneb, the ARIC Study, 1990–92
| Whites | Blacks | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Q1 (n=1,758) |
Q2 (n=1,732) |
Q3 (n=1,640) |
Q4 (n=1,592) |
Q5 (n=1,344) |
Q1 (n=259) |
Q2 (n=288) |
Q3 (n=383) |
Q4 (n=430) |
Q5 (n=674) |
|
| Median (pg/mL) | 25.1 | 32.7 | 39.1 | 46.5 | 60.2 | 25.4 | 32.5 | 39.0 | 46.6 | 63.5 |
| Range (pg/mL) | 3.2–29.3 | 29.3–35.7 | 35.7–42.4 | 42.4–51.7 | 51.7–153.1 | 2.1–29.3 | 29.3–35.7 | 35.7–42.4 | 42.4–51.7 | 51.7–179.8 |
| Selected characteristics | ||||||||||
| Age (years) | 56.4 (5.6) | 56.6 (5.6) | 56.9 (5.6) | 57.1 (5.7) | 57.6 (5.7) | 54.7 (5.6) | 54.9 (5.6) | 55.3 (5.6) | 55.5 (5.5) | 56.2 (5.8) |
| Women, % (n) | 53.4 (939) | 53.2 (922) | 53.8 (883) | 58.0 (923) | 59.4 (798) | 47.5 (123) | 54.5 (157) | 59.8 (229) | 66.3 (285) | 74.5 (502) |
| > HS education, % (n) | 36.9 (648) | 40.8 (705) | 39.7 (651) | 43.7 (695) | 41.4 (555) | 36.4 (94) | 35.7 (102) | 37.6 (144) | 37.2 (160) | 36.6 (246) |
| Current smoker, % (n) | 33.8 (594) | 22.2 (384) | 17.7 (291) | 12.2 (194) | 10.4 (140) | 42.8 (110) | 30.7 (88) | 25.9 (99) | 21.7 (93) | 18.5 (124) |
| Alcohol (g/wk) | 44.8 (97.4) | 45.0 (95.7) | 41.6 (91.7) | 35.7 (76.5) | 32.9 (80.6) | 46.5 (102.0) | 36.9 (145.9) | 22.6 (70.1) | 20.9 (91.8) | 20.4 (77.7) |
| Sport index | 2.6 (0.8) | 2.6 (0.8) | 2.6 (0.8) | 2.5 (0.8) | 2.5 (0.8) | 2.2 (0.7) | 2.2 (0.7) | 2.2 (0.7) | 2.1 (0.7) | 2.1 (0.6) |
| Fam history diabetes, % (n) | 22.5 (396) | 22.6 (391) | 20.9 (343) | 20.5 (327) | 21.5 (289) | 19.3 (50) | 26.4 (76) | 23.2 (89) | 24.9 (107) | 24.5 (165) |
| Clinical characteristics | ||||||||||
| Body mass index (kg/m2) | 26.1 (4.2) | 26.3 (4.1) | 26.9 (4.5) | 27.3 (4.7) | 28.4 (5.5) | 26.9 (5.2) | 28.5 (5.4) | 28.4 (5.0) | 29.3 (5.5) | 30.9 (6.8) |
| Waist circumference (cm) | 93.6 (12.6) | 94.0 (12.3) | 95.5 (12.9) | 96.6 (13.1) | 99.4 (14.9) | 93.0 (12.9) | 96.6 (13.8) | 96.8 (12.9) | 98.8 (13.6) | 101.6 (16.2) |
| eGFR (ml/min/1.73m2) | 94.3 (14.1) | 94.9 (14.4) | 94.6 (14.3) | 94.5 (15.4) | 92.4 (16.2) | 103.7 (17.4) | 102.8 (15.0) | 101.8 (17.3) | 102.1 (18.0) | 100.8 (18.4) |
| Systolic BP (mm Hg) | 116.2 (16.5) | 117.0 (16.8) | 118.4 (16.9) | 120.0 (16.7) | 121.2 (18.2) | 122.4 (20.8) | 121.8 (18.2) | 122.0 (17.9) | 124.2 (19.2) | 128.8 (21.0) |
| Diastolic BP (mm Hg) | 69.5 (9.4) | 70.2 (9.6) | 71.1 (9.8) | 71.9 (9.4) | 72.5 (9.8) | 74.9 (11.7) | 75.1 (10.1) | 74.4 (10.2) | 75.1 (10.1) | 77.1 (11.3) |
| BP lowering meds, % (n) | 22.8 (401) | 22.1 (383) | 23.5 (386) | 25.1 (399) | 30.7 (412) | 30.5 (79) | 37.2 (107) | 42.6 (163) | 41.3 (177) | 44.5 (300) |
| Lipid lowering meds, % (n) | 8.0 (141) | 5.7 (98) | 6.7 (110) | 6.0 (96) | 6.0 (80) | 2.8 (7) | 2.4 (7) | 4.5 (17) | 3.0 (13) | 2.2 (15) |
| Heart disease, % (n) | 4.6 (78) | 5.2 (88) | 4.7 (75) | 4.4 (69) | 5.2 (68) | 2.0 (5) | 2.8 (8) | 2.9 (11) | 3.1 (13) | 3.0 (20) |
| Blood concentration | ||||||||||
| Glucose (mg/dL)c | 100.0 (9.3) | 100.7 (9.2) | 101.1 (9.2) | 101.2 (9.4) | 102.3 (9.2) | 103.8 (17.6) | 101.5 (10.1) | 103.1 (9.1) | 103.3 (10.2) | 103.7 (9.8) |
| Insulin (mU/L)c | 19.9 (13.2) | 16.0 (5.2) | 15.6 (4.7) | 18.0 (8.6) | 19.0 (8.2) | 20.2 (6.4) | 18.7 (5.5) | 20.5 (13.9) | 17.6 (5.9) | 32.0 (28.9) |
| HbA1c (%) | 5.4 (0.3) | 5.4 (0.3) | 5.3 (0.3) | 5.3 (0.3) | 5.4 (0.3) | 5.5 (0.5) | 5.6 (0.4) | 5.6 (0.4) | 5.6 (0.4) | 5.6 (0.4) |
| HbA1c (mmol/mol) | 35.3 (3.6) | 35.1 (3.7) | 35.0 (3.5) | 34.8 (3.7) | 35.1 (3.8) | 37.1 (5.1) | 37.5 (4.5) | 37.7 (4.6) | 37.5 (4.4) | 37.9 (4.5) |
| Calcium (mg/dL) | 7.5 (2.1) | 7.6 (2.2) | 7.6 (2.1) | 7.7 (2.0) | 7.8 (2.1) | 8.2 (2.3) | 8.4 (2.2) | 8.2 (2.2) | 8.5 (2.3) | 8.7 (2.2) |
| Phosphorous (mg/dL) | 3.6 (0.5) | 3.5 (0.5) | 3.5 (0.5) | 3.5 (0.4) | 3.4 (0.5) | 3.7 (0.5) | 3.7 (0.5) | 3.6 (0.5) | 3.6 (0.5) | 3.5 (0.5) |
| HDL-cholesterol (mg/dL) | 49.2 (16.6) | 49.8 (16.1) | 50.4 (16.8) | 50.2 (16.5) | 50.4 (16.9) | 55.7 (18.1) | 56.1 (19.2) | 55.0 (17.9) | 54.7 (16.4) | 55.3 (17.0) |
| Triglycerides (mg/dL) | 137.3 (76.0) | 130.1 (73.8) | 133.2 (70.7) | 131.1 (73.1) | 135.8 (80.9) | 97.2 (48.1) | 102.8 (56.5) | 101.6 (50.3) | 105.8 (86.2) | 104.5 (69.7) |
| 25(OH)D (ng/mL) | 28.7 (9.0) | 27.5 (8.9) | 26.5 (8.3) | 25.0 (7.9) | 23.3 (8.4) | 21.9 (7.3) | 20.8 (7.4) | 19.6 (6.7) | 19.0 (7.0) | 16.9 (6.5) |
a
Presented as the mean (SD) unless otherwise noted.
b
Quintile categories of parathyroid hormone are based on the total population (white and black adults).
c
Glucose and insulin concentrations are presented irrespective of fasting time.
Q, quintile; HS, high school; eGFR, estimated glomerular filtration rate; HbA1c, glycated hemoglobin