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Top gene-level association results after discovery and replication phases
| Trait | Position | Gene | Test |
P value from
targeted sequencing |
P value from
replication sequencing |
|---|---|---|---|---|---|
| HDL-C | chr11:116701353- 116701613 |
APOC3 | VT | 1.8×10−3 | 2.1×10−5 |
| LDL-C | chr19:11200282- 11241961 |
LDLR | VT | 4.1×10−3 | 5.0×10−12 |
Association results with P <0.05 in targeted sequencing gene based analysis using variable threshold tests (VT) and replication sequencing gene based analysis using burden tests.
