Table 5.

Change in Outcome Measures at all Time Points from Increasing the Predictors from Lower to Upper Quartile^a

	Baseline SSD T1ρ pLT (0.9, 5.6)b		Baseline SSD T2 TrF (0.5, 2.2)b		Total WORMS Cartilage Lesion (0.0, 3.8)b
Outcomes	Mean	95% CI	Mean	95% CI	Mean	95% CI
Baseline (n = 51)
KOOS
Pain	−8.92	−15.4 to −2.5	−0.57	−4.5 to 3.4	−6.58	−14.8 to 1.6
Symptoms	−6.58	−13.5 to 0.4	1.08	−3.2 to 5.3	−9.57	−19.1 to 0.0
ADL	−9.12	−15.2 to −3.0	−0.88	−4.6 to 2.8	−8.25	−16.6 to 0.1
Sports	−13.36	−24.7 to −2.0	0.66	−6.2 to 7.6	2.76	−12.6 to 18.1
QOL	−10.54	−19.9 to −1.2	3.31	−2.4 to 9.0	−7.32	−20.1 to 5.4
6-month Follow-up (n = 46)
KOOS
Pain	−5.50	−10.6 to −0.4	0.39	−2.7 to 3.5	−8.45	−15.7 to −1.2
Symptoms	−5.42	−11.7 to 0.9	0.73	−3.3 to 4.8	−5.37	−14.9 to 4.2
ADL	−0.49	−4.3 to 3.4	−1.05	−3.2 to 1.2	−7.65	−12.8 to −2.4
Sports	−3.67	−12.9 to 5.6	2.56	−3.1 to 8.2	−12.02	−24.5 to 0.4
QOL	−2.52	−9.9 to 4.9	4.29	−0.8 to 9.4	−10.58	−21.2 to 0.1
1-year Follow-up (n = 42)
KOOS
Pain	−6.51	−10.8 to −2.3	−0.62	−3.2 to 2.0	−6.64	−12.4 to −0.9
Symptoms	−6.15	−11.5 to −0.8	−0.94	−4.4 to 2.5	−5.22	−12.9 to 2.5
ADL	−2.62	−5.0 to −0.2	−1.76	−3.3 to −0.2	−2.00	−5.3 to 1.3
Sports	−6.50	−13.8 to 0.8	−0.99	−5.7 to 3.7	−2.37	−12.2 to 7.5
QOL	−12.6	−21.0 to −4.2	0.92	−4.8 to 6.6	−2.88	−14.8 to 9.1
Marx	−2.33	−4.0 to −0.7	0.21	−1.1 to 1.5	1.89	−0.5 to 4.2

^aSSD, side-to-side difference pLT, posterolateral tibia; TrF, femoral trochlea; WORMS, Whole-Organ MRI Scoring; CI, confidence interval; KOOS, Knee-Injury and Osteoarthritis Outcome Score; ADL, activities of daily living; QOL, knee-related quality-of-life. Bold denotes clinically meaningful changes.

^bInterquartile Range.