Figure 7. The function of endothelial Kir channels is unaffected in angiotensin II‐induced hypertension .

Kir currents were recorded using the perforated patch configuration of the patch‐clamp technique in ECs from third‐order mesenteric arteries. Arterial diameter measurements were performed in third‐order mesenteric arteries constricted by intravascular pressure (80 mmHg). A, Ba²⁺‐sensitive Kir currents in the ECs from normal (NT) and hypertensive (HT) mice. The bar graph summarizes Kir current densities at −140 mV (n = 8–10 cells; P = 0.8403 using Student's t test). B, a representative diameter trace in a third‐order mesenteric artery from a HT mouse. The bar graph (C) shows summarized diameter data in the arteries from NT and HT mice (n = 4–9 arteries; P = 0.5895 using Student's unpaired t test).