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. 2016 Feb 16;30(2):117–121. doi: 10.1016/j.sjopt.2016.02.001

Table 1.

Ocular involvement in systemic lupus erythematosus.

Structure Clinical findings
Orbital and external eye disease Discoid lupus-type rash over the eyelids
Panniculitis
Orbital masses
Periorbital edema
Orbital myositis
Orbital vasculitis, acute orbital ischemia and infarction



Conjunctival involvement Conjunctivitis



Corneal involvement Dry eye syndrome
Recurrent corneal erosions
Peripheral corneal infiltrates
Peripheral ulcerative keratitis
Interstitial keratitis
Endotheliitis
Keratoconus



Sclera and Episclera Scleritis
Episcleritis



Uveal involvement Anterior uveitis



Retinal involvement Lupus retinopathy (cotton wool spots, intraretinal hemorrhages, and vascular tortuosity)
Retinal hard exudates
Retinal vasculitis
Retinal artery and/or vein occlusion
Arteriolar narrowing and arteriovenous crossing changes
Macular pigmentary mottling
Retinal scarring
Macular infarction



Choroidal involvement Central serous chorioretinopathy



Neuro-ophthalmic findings Optic nerve involvement
Optic neuritis
Ischemic optic neuropathy
Papilledema
Central nervous system vasculitis
Internuclear ophthalmoplegia
Nystagmus
Cranial nerve palsies
Homonymous hemianopia