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. 2016 Jun 15;6:135. doi: 10.3389/fonc.2016.00135

Table 2.

Experimental data compared to calculated values determined by dynamic bonded cumomer modeling (mmol/L-cell/h).

Reaction Exp. Flux (mmol/L-cell/h) Calculated flux (mmol/L-cell/h)
Oxygen consumption MRO2 36 32
Glucose uptake 91.0 85
Pyruvate to lactate 155.0 150
Glutamine uptake 5.0 a
Glutamate concentration 8.6 mM 9.2 mM

aThe flux was not estimated, as glutamine is consumed in numerous reactions we did not study here. This research was originally published in Journal of Biological Chemistry. Shestov et al. (14). The American Society for Biochemistry and Molecular Biology.