Table 2.
Characteristic of 22 integron-positive Aeromonas isolates.
| Strain | Aeromonas spp. | Year | Species | Farm | Class 1 integron gene cassettes | Resistance genes | QRDR mutation | Antimicrobial resistance profile | |
|---|---|---|---|---|---|---|---|---|---|
| GyrA | ParC | ||||||||
| A15 | A. hydrophila | 1998 | Fish (Channa argus) | FF6 | dfrA17 | tetA | Ile83 | Ser80 | AMP\S3\SXT\RD\NA\TE\C\S |
| A16 | A. hydrophila | 1998 | Fish (C. argus) | FF6 | dfrA17 | tetA | Ile83 | Ser80 | AMP\S3\SXT\RD\NA\TE\C\S |
| A36 | A. hydrophila | 2004 | Ornamental fish (Crypinus carpiod) | OF1 | drfA12-orfF-aadA2 | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\OFL\TE\DO\C\S | |
| A25 | A. hydrophila | 2004 | Turtle (Chelydra serpentine) | TF2 | drfA12-orfF-aadA2 | blaCTX−M−3, blaTEM−1, aac(6′)-Ib-cr | Ile83 | Ile80 | AMP\CTX\S3\SXT\RD\NA\CIP\NOR\OFL\TE\C\AK\S |
| A21 | A. hydrophila | 2003 | Turtle (Mauremys mutica) | TF3 | drfA12-orfF-aadA2 | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\NOR\OFL\TE\DO\C\S | |
| A27 | A. hydrophila | 2003 | Turtle (M. mutica) | TF3 | drfA12-orfF-aadA2 | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\TE\DO\C\S | |
| A23 | A. hydrophila | 2003 | Turtle (M. mutica) | TF4 | drfA12-orfF-aadA2 | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\NOR\OFL\TE\DO\C\S | |
| A26 | A. hydrophila | 2003 | Turtle (C. serpentine) | TF4 | drfA12-orfF-aadA2 | aac(6′)-Ib | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\NOR\OFL\TE\ DO\C\S |
| A03 | A. hydrophila | 1996 | Fish (Carassius auratus) | FF1 | drfA12-orfF-aadA2 | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\OFL\TE\DO\C\S | |
| A19 | A.veronii | 2001 | Fish (Siniperca chuatsi) | FF9 | drfA12-orfF-aadA2 | Ile83 | Ile80 | AMP\S3\SXT\NA\S | |
| A47 | A. hydrophila | 2005 | Fish (Tenualosa reevesii) | FF16 | drfA12-orfF-aadA2 | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\NOR\OFL\TE\DO\C\S | |
| A72 | A. hydrophila | 2006 | Fish (Cirrhinus molitorella) | FF18 | drfA12-orfF-aadA2 | Ile83 | Ser80 | AMP\S3\SXT\NA\TE\S | |
| A78 | A. hydrophila | 2007 | Fish (Oreochromis niloticus) | FF22 | drfA12-orfF-aadA2 | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\NOR\OFL\TE\DO\C\S | |
| A01 | A. sobria | 1995 | Shrimp (Macrobrachium rosenbergii) | SF1 | drfA12-orfF-aadA2 | Val83 | Ile80 | AMP\S3\SXT\RD\NA\TE\S | |
| A41 | A. veronii | 2004 | Ornamental fish (C. auratus) | OF2 | drfA12-orfF-aadA2, drfA17 | Val83 | Ile80 | AMP\S3\SXT\RD\NA\ NOR\OFL\TE\ DO\AK\S | |
| A42 | A. veronii | 2004 | Fish (Megalobrama terminalis) | FF11 | drfA12-orfF-aadA2, catB3, arr-3 | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\S | |
| A24 | A. hydrophila | 2003 | Turtle (C. serpentine) | TF2 | drfA12-orfF-aadA2, catB3, arr-3 | aac(6′)-Ib | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\CIP\NOR\OFL\TE\ DO\S |
| A33 | A. hydrophila | 2004 | Giant salamander (Andrias davidianus) | AF1 | aac(6′)-II-blaOXA−21-cat3 | Ile83 | Ile80 | AMP\S3\SXT\NA\TE\S | |
| A83 | A. hydrophila | 2007 | Turtle (Pelodiscus sinensis) | TF10 | drfA12-orfF, catB3 | Ile83 | Arg80 | AMP\S3\SXT\RD\NA\CIP\NOR\OFL\C\S | |
| A84 | A. hydrophila | 2007 | Turtle (Pelodiscus sinensis) | TF10 | drfA12-orfF, catB3 | aac(6′)-Ib-cr | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\CIP\NOR\OFL\C\S |
| A22 | A. hydrophila | 2004 | Turtle (C. serpentine) | TF4 | No insert | blaTEM−1, aac(6′)-Ib-cr | Ile83 | Ile80 | AMP\CTX\S3\SXT\RD\NA\CIP\TE\AK\S |
| A38 | A. hydrophila | 2004 | Giant salamander (A. davidianus) | AF1 | ND | Ile83 | Ile80 | AMP\S3\SXT\RD\NA\CIP\NOR\OFL\TE\ DO\C\S | |
ND, not determined; FF, fish farm; OF, ornamental fish farm; TF, turtle farm; AF, amphibian farm; SF, shrimp farm; QRDR, quinolone resistance-determining regions; Ser, serine; Ile, iosleucine; Val, valine; Arg, arginine; AMP, ampicillin; CTX, cefotaxime; S3, sulfonamides; SXT, trimethoprim/sulfamethoxazole; RD, rifampin; NA, nalidixic acid; CIP, ciprofloxacin; NOR, norfloxacin; OFL, ofloxacin; TE, tetracycline; DO, doxycycline; S, streptomycin; AK, amikacin; C, chloramphenicol.