Figure 3.

Assessment transcripts of hypoxia-responsive genes: mRNA levels of; (A) Vascular endothelial growth factor (VEGF) and; (B) carbonic anhydrase 9 (CA9) were analyzed in C4-2B cells growing under hypoxia (■) or normoxia (□). *p < 0.05 when data at 2% O2 are compared to values at 20% O2 at the same time point; #p < 0.05 when data at 2% O2 or 20% O2 are compared to a previous time point within the same O2%; and &p < 0.05 when a specific data point is compared to the point at day 0 within the same O2%.