Table 1.
Abbreviations used.
ACTH | Adrenocorticotrophic hormone, corticotrophin |
AgRP | Agouti-related peptide |
AKR1B7 | Aldo-keto reductase family 1 member B7 |
AKR1C3 | Aldo-keto reductase family 1 member C3, type 5 17β-HSD |
ANP | Atrial natriuretic peptide |
AP-1 | Activator protein 1 (c-fos, c-jun heterodimeric transcription factor) |
APCC | Aldosterone producing cell clusters |
ARNTL | Aryl hydrocarbon receptor nuclear translocator-like protein 1, = BMAL |
AsP | Adrenal secretory protease |
AT1R | Angiotensin II type 1 receptor |
AZ1 | Adrenocortical zonation factor |
BMAL | basic helix-loop-helix/PER-ARNT-SIM (bHLH/PAS) transcription factor, = ARNTL, MOP3 |
BMP | Bone morphogenetic protein |
3β-HSD | 3β-hydroxysteroid dehydrogenase |
11β-HSD | 11β-hydroxysteroid dehydrogenase |
20α-HSD | 20α-hydroxysteroid dehydrogenase |
18-OH-DOC | 18-hydroxydeoxycorticosterone |
BrdU | Bromodeoxyuridine |
c-AMP | cyclic adenosine monophosphate |
c-fos | See AP1 |
c-jun | See AP1 |
CLOCK | Circadian Locomotor Output Cycle Kaput gene |
CRF | Corticotrophin releasing factor |
Cry2 | Cryptochrome circadian clock 2 gene |
Cyt B5 | Cytochrome B5 |
CYP2D16 | Cytochrome P4502D16 |
CYP11A | Cytochrome P450scc(cholesterol side chain cleavage) |
CYP11B1 | Cytochrome P45011B1(11β-hydroxylase) |
CYP11B2 | Cytochrome P45011B2 (aldosterone synthase) |
CYP17 | Cytochrome P45017(17-hydroxylase) |
CYP21 | Cytochrome P45021(21-hydroxylase) |
Dab-2 | Disabled homolog-2, = DOC2, C9, p96/p67 |
DACH-1 | Dachshund family transcription factor |
DAX1 | Dosage sensitive reversal adrenal hypoplasia critical region, chromosome X, = NrOb1 |
DHCR24 | 24 dehydrocholesterol reductase, seladin-1 |
DHEA | Dehydroepiandrosterone |
Eph | Ephrin receptor |
ERK | Extracellular signal regulated kinase, = MAPK |
bFGF | basic Fibroblast growth factor |
GATA | GATA sequence binding transcription factor |
Gli1 | Glioblastoma 1 |
Grx | Glutaredoxin |
GPCR | G protein coupled receptor |
IGIF | Interferon-γ inducing factor = IL 18 or IL-1γ |
IGF | Insulin-like growth factor |
IL | Interleukin |
IP3 | Inositol trisphosphate |
IZA | Inner zone antigen, = PGRMC-1, Sigma 2 receptor |
Ki67 | Antigen K67, = MKI67 |
LEF1 | Lymphoid enhancer-binding factor 1 |
LHR | Luteinizing hormone receptor |
MC2R/MC5R | Melanocortin receptor 2/5 (ACTH/ melanotrophin receptors respectively) |
MAPK | Mitogen activated protein kinase, = ERK |
MnSOD | Manganese euperoxide dismutase |
MRAP | Melanocortin-2-receptor accessory protein |
α-MSH | α-melanocyte stimulating hormone |
Nek2 | NMA (never in mitosis gene a) related expressed kinase 2 |
NGFIB | nerve growth factor induced clone B; |
NPY | Neuropeptide Y |
Notch1,2 | Notch (Drosophila) homolog 1,2 |
NOV | Nephroblastoma overexpressed, = CCN3 |
NURR-1 | Nur-related factor 1 |
OAT | Organic anion transporter |
OATP | Organic anion transporter polypeptide |
ODC | Ornithine decarboxylase |
Per | Period component of Per/Tim (timeless) heterodimer |
Pik3c2g | Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide gene |
PKC | Protein kinase C |
Prkar1α | Type 1 α-regulatory subunit of cAMP dependent protein kinase |
PPARγ | Peroxisome proliferator activated receptorγ |
Pref1 | Preadipocyte factor 1, = dlk1 (delta like homolog 1) |
Prx | Peroxiredoxin |
ROS | Reactive oxygen species |
R26 YFP | Rosa 26 yellow fluorescent protein |
Rev-Erbα) | Nuclear receptor subfamily 1, group D, member 1, NR1D1 |
SCN | Suprachiasmatic nucleus |
SF1 | Steroidogenic factor 1 (also AD4BP, NR5A1) |
Shh | Sonic hedgehog (hedgehog signaling pathway component) |
SLC27A2 | Solute carrier family 27 (fatty acid transporter), member 2 |
StAR | Steroidogenic acute regulatory protein |
SULT2A1 | Steroid sulfotransferase |
TASK1,3 | TWIK-related acid-sensitive K +channels, KCNK3 and 9 (members of family of two-pore domain potassium channels) |
TGFβ | Transforming growth factor |
TNF | Tumor necrosis factor |
Trx | Thioredoxin |
TrxR | Thioredoxin reductase |
TSPAN12 | Tetraspanin 12 |
Ucn3 | Urocortin 3 |
VIP | Vasoactive intestinal peptide |
Wnt | Wingless related integration site |
ZU | Undifferentiated zone |