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. 2016 May 26;98(6):1101–1113. doi: 10.1016/j.ajhg.2016.03.028

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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miTmc Lowers Mechanotransduction Currents in Tmc1^Bth/− Mice

(A) Families of mechanotransduction currents were recorded from eight different IHCs (P8–P10) under four different conditions. Currents were evoked by step hair-bundle deflections that ranged in amplitude from −0.2 to 1 μm.

(B) Scatter plot shows maximal mechanotransduction currents recorded from 74 IHCs (open symbols) under four different conditions. Filled symbols indicate the mean ± SE (box) and SD (bars) for each condition. The number of cells for each condition is indicated at the bottom.