Table 1.
Association of the Top Candidate Causal SNPs at Chromosome 14q32.33 with Endometrial Cancer Risk
| SNP | Position (Build 19) | Minor allele | Common allele | MAFa | OR (95% CI)b | p value | r2to rs2498796 | Likelihood ratioc |
|---|---|---|---|---|---|---|---|---|
| rs2498794 | 105245251 | G | A | 0.48 | 1.13 (1.09–1.17) | 8.7 × 10−9 | 0.43 | 1 |
| rs2494737 | 105246325 | A | T | 0.30 | 1.13 (1.08–1.17) | 2.5 × 10−7 | 0.83 | 26 |
| rs2498796 | 105243220 | A | G | 0.30 | 1.11 (1.07–1.16) | 1.2 × 10−6 | -- | 120 |
a
Minor (risk-increasing) allele frequency.
b
OR for the effect allele.
c
Ratio of the likelihood of rs2498794 to the likelihood of this SNP.