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. 2016 May 10;5(2):80–85. doi: 10.1016/j.jbo.2016.05.003

Fig. 3.

Fig. 3

Effects of lncRNA-UCA1 on the biological behaviors of osteosarcoma cells. (A) qRT-PCR analysis confirmed increased UCA1 expression in HOS cells transfected with pcDNA-UCA1, and decreased UCA1 expression in MG-63 cells transfected with si-UCA1. **P<0.01. (B) MTT assay showed that lncRNA-UCA1 promoted cell proliferation. **P<0.01. (C) Flow cytometric analysis indicated that lncRNA-UCA1 reduced cell apoptosis. (D, E) Down-regulation of lncRNA-UCA1 impeded the invasion/migration of MG-63 cells, while up-regulation of lncRNA-UCA1 promoted cell invasion/migration ability in HOS cells. **p<0.01.