Table 3.
Haplotype frequencies of INS and ERBB3 in patients with T1D and healthy controls.
| Gene | Blocks | Haplotype | Haplotype frequency |
OR (95% CI) | P value | Pcorr | |
|---|---|---|---|---|---|---|---|
| T1D n = 364 | Controls n = 719 | ||||||
| INS | rs689/rs7924316/rs1004446/rs3741208 | ATAG | 0.014 | 0.042 | 0.32 (0.10–0.84) | 0.005 | NS |
| TTGG | 0.558 | 0.486 | 1.34 (1.03–1.73) | 0.01 | NS | ||
| ERBB3 | rs2292239/rs705708/rs2292238 | GGA | 0.417 | 0.502 | 0.71 (0.55–0.92) | 0.0006 | 0.03 |
| TGA | 0.227 | 0.161 | 1.53 (1.10–2.13) | 0.0006 | 0.03 | ||
Only significant results are shown. Abbreviations: T1D: type 1 diabetes; OR: odds ratio; 95% CI: 95% confidence interval; Pcorr: P value after Bonferroni correction (n = 55).