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. 2016 Jun 11;32(12):i288–i296. doi: 10.1093/bioinformatics/btw274

Table 4.

Inferred parameters for the Th17 core network using static network structure

j Mechanism Rate parameter
1 Basal activation of BATF 0.122
2 Basal activation of STAT3 0.473
3 Basal activation of IRF4 0.011
4 Basal activation of MAF 0.001
7 STAT3 activates IRF4 4.069
16 BATF and IRF activate RORC 0.310
17 BATF and IRF activate MAF 12.214
20 Degradation of BATF 0.557
21 Degradation of STAT3 2.995
22 Degradation of IRF4 1.000
23 Degradation of RORC 0.501
24 Degradation of MAF 12.560

In the statistical model, the parameters α and β have the values, 0.0001 and 0.035, respectively.