Table 3. Altered nodal topology associated with depression severity in patient group.

Node	Brodmann Area#	Direction	p-value (FDR corrected)
Betweenness Centrality
L- Inferior parietal	BA 39, CEN	High < Low	0.003
L- lateral orbitofrontal	BA 11, N/A	High < Low	0.005
L- posterior cingulate	BA 23 & 24, DMN	High > Low	0.048
R- Inferior parietal	BA 39, CEN	High > Low	0.028
R- posterior cingulate	BA 23 & 24, DMN	High > Low	0.022
Degree Centrality
L- medial orbitofrontal	BA 11 & 25, DMN	High > Low	0.025
R- superior parietal	BA 5 & 7, CEN	High > Low	0.022
R- superior temporal	BA 41 & 42, N/A	High < Low	0.041
Efficiency
L- cuneus	BA 17, N/A	High > Low	0.045
L- pars opercularis frontal	BA 44, CEN	High < Low	0.046
L- rostral middle frontal	BA 9, CEN	High < Low	0.008
R- middle temporal	BA 31, DMN	High > Low	0.024

^#Gyral-based parcellation was approximately assigned to Brodmann areas, and components of large scale network.