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. 2016 Jun 1;4(11):e12785. doi: 10.14814/phy2.12785

Figure 1.

Figure 1

Skeletal muscle gene expression of key regulators of mitochondrial biogenesis and function. Expression of individual genes involved in mitochondrial biogenesis and function was determined by quantitative RT‐PCR before (white bars) and after (black bars) corn oil or n‐3 PUFA treatment (n = 10 per group). The expression of genes of interest was normalized to the expression of RPLP0. *Value significantly different from corresponding value in the control group (P < 0.05 by post‐hoc Tukey's test). †Value significantly different from corresponding value before treatment (P < 0.01 by post hoc Tukey's test). # ANOVA revealed a significant main effect of group (P < 0.05). UPC3,UQCRC1,CS,PPARGC1A,PPARA, PDHA1,CPT1B,UQCRC2,COX4I1, and COX5B are presented as mean ± SEM; are presented as median ± quartiles. UCP3, uncoupling protein 3; UQCRC1, ubiquinol‐cytochrome c reductase core protein I; CS, citrate synthase; PPARGC1A, peroxisome proliferator‐activated receptor gamma coactivator 1 alpha; PPARA, peroxisome proliferator‐activated receptor alpha; PDHA1, pyruvate dehydrogenase (lipoamide) alpha 1; CPT1B, carnitine palmitoyltransferase 1B; UQCRC2, ubiquinol‐cytochrome c reductase core protein II;COX4I1, cytochrome c oxidase subunit 4I1; COX5B, cytochrome c oxidase subunit 5B.